Sibutramine hydrochloride

Name: Sibutramine hydrochloride
Brand: Tocris Bioscience
SKU: 2290

Cat. No. 2290 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2290 has been discontinued.

View all 5-HT Transporters products.

说明： 5-HT and NA reuptake inhibitor (SNRI)

别名： BTS 54-524

化学名： 1-(4-Chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)cyclobutanemethanamine hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献 (1)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Sibutramine hydrochloride

Sibutramine hydrochloride is a 5-HT and noradrenalin re-uptake inhibitor (SNRI). Produces weight loss in rats via inhibition of food intake and increased energy expenditure. Antidepressant.

技术数据 for Sibutramine hydrochloride

分子量	316.31
公式	C₁₇H₂₆NCl.HCl
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	84485-00-7
PubChem ID	64764
InChI Key	UWAOJIWUVCMBAZ-UHFFFAOYSA-N
Smiles	ClC1=CC=C(C2(CCC2)C(CC(C)C)N(C)C)C=C1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Sibutramine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Sibutramine hydrochloride

参考文献是支持产品生物活性的出版物。

Jackson et al (1997) Comparison of the effects of sibutr. and other monoamine reuptake inhibitors on food intake in the rat. Br.J.Pharmacol. 121 1758 PMID: 9283714

Gundlah et al (1997) In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutr. is a reuptake inhibitor. J.Pharmacol.Exp.Ther. 283 581 PMID: 9353373

Buckett et al (1988) The pharmacology of sibutr. hydrochloride (BTS 54524), a new antidepressant which induces rapid noradrenergic down-regulation. Prog.Neuro-Psychopharm.Biol.Psychiat. 12 575

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关键词: Sibutramine hydrochloride, Sibutramine hydrochloride supplier, 5-HT, noradrenalin, reuptake, inhibitors, inhibits, SNRI, Noradrenalin, Transporter, NET, Adrenergic, Transporters, Monoamine, Neurotransmitter, Serotonin, SERT, 5-Hydroxytryptamine, BTS54524, noradrenaline, BTS, 54-524, 2290, Tocris Bioscience

1 篇 Sibutramine hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Sibutramine hydrochloride 的部分引用包括：

Yoshida et al (2015) Study on health hazards through medicines purchased on the Internet: a cross-sectional investigation of the quality of anti-obesity medicines containing crude drugs as active ingredients. PLoS One 15 430 PMID: 26637485