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Silibinin

Cat. No. 0637 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0637 has been discontinued.

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说明： Induces G1 arrest
化学名： [2R-[2a,3b,6(2R*,3R*)]]-2-[2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one
说明书
引用文献
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文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for Silibinin

The active principle from Silybum marianum. Used for treatment of liver damage.

技术数据 for Silibinin

分子量 482.44
储存 Store at RT
CAS Number 22888-70-6

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Silibinin

分析证书目前不在网上提供。
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化学品安全技术说明书

参考文献 for Silibinin

参考文献是支持产品生物活性的出版物。

Sonnenbichler et al (1986) Stimulatory effect of silbinin on the DNA synthesis in partially hepatectomized rat livers: non-response in hematoma and other malign cell lines. Biochem.Pharmacol. 35 538 PMID: 3004503

Sonnenbichler et al (1999) Stimulatory effects of silibinin and silicristin from the milk thistle silybum marianum on kidney cells. J.Pharmacol.Exp.Ther. 290 1375 PMID: 10454517

Zi and Agarwal (1999) Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implication for prostate cancer intervention. Proc.Natl.Acad.Sci.U.S.A. 96 7490 PMID: 10377442

Martindale 29th Ed. 1613

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关键词: Silibinin, Silibinin supplier, Cell, Cycle, Inhibitors, 0637, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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Cell Cycle and DNA Damage Research Product Guide

Cell Cycle and DNA Damage Research Product Guide

This product guide provides a review of the cell cycle and DNA damage research area and lists over 150 products, including research tools for:

  • Cell Cycle and Mitosis
  • DNA Damage Repair
  • Targeted Protein Degradation
  • Ubiquitin Proteasome Pathway
  • Chemotherapy Targets
Cell Cycle & DNA Damage Repair Poster

Cell Cycle & DNA Damage Repair Poster

In normal cells, each stage of the cell cycle is tightly regulated, however in cancer cells many genes and proteins that are involved in the regulation of the cell cycle are mutated or over expressed. This poster summarizes the stages of the cell cycle and DNA repair. It also highlights strategies for enhancing replicative stress in cancer cells to force mitotic catastrophe and cell death.