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StRIP16

Cat. No. 6575 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6575 has been discontinued.

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说明： Rab8a GTPase-binding stapled peptide
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for StRIP16

StRIP16 is a rab8a GTPase-binding stapled peptide (Kd = 12.7 μM). Cell permeable; localizes to the endomembrane system.

技术数据 for StRIP16

分子量 2300.61
公式 C116H154N24O26
序列 DNEXQWFXYHLXFFNXV

(Modifications: Asp-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-4 and X-8 stapled together with a double bond, X-12 and X-16 stapled together with a double bond, Val-17 = C-terminal amide)
储存 Store at -20°C
Smiles CC(C[C@@H](C(N[C@]1(CCC/C=C/CCC[C@](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)CC(N)=O)=O)(C(N[C@H](C(N)=O)C(C)C)=O)C)C)=O)NC([C@@H](NC([C@@H](NC([C@@]4(CCC/C=C/CCC[C@](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)NC(C)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N4)=O)CC5=CC=CC=C5)=O)CC6=CNC7=CC=CC=C67)=O)CCC(N)=O)=O)C)C)=O)CC8=CC=C(C=C8)O)=O)CC9=CN=CN9)=O)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for StRIP16

参考文献是支持产品生物活性的出版物。

Cromm et al (2016) Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase. ACS Chem.Biol. 11 2375 PMID: 27336832

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关键词: StRIP16, StRIP16 supplier, RAb8a, binding, stapled, peptides, GTPase, binds, cell-permeable, Other, Small, Monomeric, GTPases, Stapled, Peptides, 6575, Tocris Bioscience

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