Strychnine hydrochloride

Discontinued Product

2785 has been discontinued.

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说明: Competitive glycine receptor antagonist
化学名: Strychnidin-10-one hydrochloride
纯度: ≥98% (HPLC)
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生物活性 for Strychnine hydrochloride

Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α7 receptors and non-competitive antagonism at α4β2 receptors.

技术数据 for Strychnine hydrochloride

分子量 370.87
公式 C21H22N2O2.HCl
储存 Store at RT
纯度 ≥98% (HPLC)
CAS Number 1421-86-9
Smiles [H][C@]45C[C@]6([H])[C@@]2([H])C7CC(N(C2[C@]34CCN5CC6=CCO7)C1=C3C=CC=C1)=O.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Strychnine hydrochloride

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参考文献 for Strychnine hydrochloride

参考文献是支持产品生物活性的出版物。

Mataubayashi et al (1998) Strychnine: a potent competitive antagonist of α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons. J.Pharmacol.Exp.Ther. 284 904 PMID: 9495848

Betz et al (2006) Glycine receptors: recent insights into their structural organization and functional diversity. J.Neurochem. 67 1600

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关键词: Strychnine hydrochloride, Strychnine hydrochloride supplier, Competitive, glycine, receptors, antagonists, Nicotinic, GlyR, Acetylcholine, Non-Selective, Subtypes, nAChR, a7, α7, alpha7, α4β2, a4b2, Glycine, Receptors, (Non-selective), 2785, Tocris Bioscience

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