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Swainsonine

Cat. No. 3208 3 篇引用文献 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Inhibitor of α-mannosidase II
化学名： (1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol
说明书
引用文献 (3)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Swainsonine

Swainsonine is an inhibitor of α-mannosidase II which inhibits glycoprotein processing. Displays anticancer and immune modulatory properties.

技术数据 for Swainsonine

分子量 173.21
公式 C8H15NO3
储存 Store at -20°C
CAS Number 72741-87-8
PubChem ID 51683
InChI Key FXUAIOOAOAVCGD-WCTZXXKLSA-N
Smiles O[C@@H]2[C@H](O)CN1CCC[C@@H](O)[C@@]12[H]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Swainsonine

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 8.66 50

制备储备液 for Swainsonine

以下数据基于产品分子量 173.21。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 11.55 mL 57.73 mL 115.47 mL
2.5 mM 2.31 mL 11.55 mL 23.09 mL
5 mM 1.15 mL 5.77 mL 11.55 mL
25 mM 0.23 mL 1.15 mL 2.31 mL

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产品说明书 for Swainsonine

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Swainsonine

参考文献是支持产品生物活性的出版物。

Tulsiani et al (1982) Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of golgi mannosidase II. J.Biol.Chem. 257 7936 PMID: 6806288

Olden et al (1991) The potential importance of swainsonine in therapy for cancers and immunology. Pharmacol.Ther. 50 285 PMID: 1754603

Sun et al (2007) Inhibition of the growth of human gastric carcinoma in vivo and in vitro by swainsonine. Phytomedicine 14 353 PMID: 17097281

If you know of a relevant reference for Swainsonine, please let us know.

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关键词: Swainsonine, Swainsonine supplier, inhibitors, inhibits, α-mannosidase, alpha-mannosidase, II, Glycosylases, Carbohydrate, Metabolism, 3208, Tocris Bioscience

3 篇 Swainsonine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Swainsonine 的部分引用包括：

Skrenkova et al (2018) N-Glycosylation Regulates the Trafficking and Surface Mobility of GluN3A-Containing NMDA Receptors. Front Mol Neurosci 11 188 PMID: 29915530

Tareen et al (2014) Design of a novel integration-deficient lentivector technology that incorporates genetic and posttranslational elements to target human dendritic cells. Mol Ther 22 575 PMID: 24419083

Nacev et al (2011) The antifungal drug itracon. inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. J Biol Chem 286 44045 PMID: 22025615

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