Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewT3 is a thyroid hormone. Promotes differentiation of oligodendroglial precursor cells in neonatal rats and promotes maturation of hiPSC-derived cardiomyocytes. Also specifies cone cell subtype in retinal cell differentiation protocols. T3 is used in protocols to generate cortical spheroids from hPSCs.
T3 synthesized to Ancillary Material Grade also available.
For more information about how T3 may be used, see our protocol: Generation of β cells from hPSCs
分子量 | 650.97 |
公式 | C15H12I3NO4 |
储存 | Store at -20°C |
纯度 | ≥98% (HPLC) |
CAS Number | 6893-02-3 |
PubChem ID | 5920 |
InChI Key | AUYYCJSJGJYCDS-LBPRGKRZSA-N |
Smiles | N[C@H](C(O)=O)CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(C=C2)O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
DMSO | 32.55 | 50 |
以下数据基于产品分子量 650.97。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.5 mM | 3.07 mL | 15.36 mL | 30.72 mL |
2.5 mM | 0.61 mL | 3.07 mL | 6.14 mL |
5 mM | 0.31 mL | 1.54 mL | 3.07 mL |
25 mM | 0.06 mL | 0.31 mL | 0.61 mL |
参考文献是支持产品生物活性的出版物。
Marta et al (1998) Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system. J.Neurosci.Res. 53 251 PMID: 9671982
Madhavan et al (2018) Induction of myelinating oligodendrocytes in human cortical spheroids. Nat Methods. 15 700 PMID: 30046099
Yang et al (2014) Tri-iodo-L-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells. J.Mol.CellCardiol. 72 296 PMID: 24735830
Eldred et al (2018) Thyroid hormone signaling specifies cone subtypes in human retinal organoids. Science 362 eaau6348 PMID: 30309916
Surendran et al (2022) An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells. STAR Protoc. 3 101803 PMID: 36386870
If you know of a relevant reference for T3, please let us know.
关键词: T3, T3 supplier, triiodothyronine, thyroid, hormone, oligodendroglial, precursors, differentiation, cortical, organoids, cardiomyocyte, maturation, retinal, pigment, epithelial, cells, RPE, Other, Nuclear, Receptors, Differentiation, Products, Cardiomyocyte, Stem, Cells, Retinal, 6666, Tocris Bioscience
目前没有该产品的评论。 Be the first to review T3 and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image