T3

Pricing Availability   Qty
说明: Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
化学名: O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
纯度: ≥98% (HPLC)
说明书
引用文献
评论
实验方案 (1)

生物活性 for T3

T3 is a thyroid hormone. Promotes differentiation of oligodendroglial precursor cells in neonatal rats and promotes maturation of hiPSC-derived cardiomyocytes. Also specifies cone cell subtype in retinal cell differentiation protocols. T3 is used in protocols to generate cortical spheroids from hPSCs.

T3 synthesized to Ancillary Material Grade also available.

For more information about how T3 may be used, see our protocol: Generation of β cells from hPSCs

技术数据 for T3

分子量 650.97
公式 C15H12I3NO4
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 6893-02-3
PubChem ID 5920
InChI Key AUYYCJSJGJYCDS-LBPRGKRZSA-N
Smiles N[C@H](C(O)=O)CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(C=C2)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for T3

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 32.55 50

制备储备液 for T3

以下数据基于产品分子量 650.97。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 3.07 mL 15.36 mL 30.72 mL
2.5 mM 0.61 mL 3.07 mL 6.14 mL
5 mM 0.31 mL 1.54 mL 3.07 mL
25 mM 0.06 mL 0.31 mL 0.61 mL

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产品说明书 for T3

分析证书/产品说明书
选择另一批次:

参考文献 for T3

参考文献是支持产品生物活性的出版物。

Marta et al (1998) Sustained neonatal hyperthyroidism in the rat affects myelination in the central nervous system. J.Neurosci.Res. 53 251 PMID: 9671982

Madhavan et al (2018) Induction of myelinating oligodendrocytes in human cortical spheroids. Nat Methods. 15 700 PMID: 30046099

Yang et al (2014) Tri-iodo-L-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells. J.Mol.CellCardiol. 72 296 PMID: 24735830

Eldred et al (2018) Thyroid hormone signaling specifies cone subtypes in human retinal organoids. Science 362 eaau6348 PMID: 30309916

Surendran et al (2022) An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells. STAR Protoc. 3 101803 PMID: 36386870


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关键词: T3, T3 supplier, triiodothyronine, thyroid, hormone, oligodendroglial, precursors, differentiation, cortical, organoids, cardiomyocyte, maturation, retinal, pigment, epithelial, cells, RPE, Other, Nuclear, Receptors, Differentiation, Products, Cardiomyocyte, Stem, Cells, Retinal, 6666, Tocris Bioscience

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T3 实验方案

以下实验方案包含使用 T3(目录编号 6666)的更多信息。