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Submit ReviewTacrine hydrochloride is a potent cholinesterase inhibitor, a cognition enhancer in vivo.
分子量 | 234.73 |
公式 | C13H14N2.HCl |
储存 | Desiccate at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 1684-40-8 |
PubChem ID | 15517 |
InChI Key | ZUFVXZVXEJHHBN-UHFFFAOYSA-N |
Smiles | Cl.NC1=C2CCCCC2=NC2=CC=CC=C12 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Freeman and Dawson (1991) Tacrine: a pharmacological review. Prog.Neurobiol. 36 257 PMID: 1714613
Osborne and Christie (1996) Tetrahydro-9-aminoacridine has mixed actions on muscarinic currents and blocks opioid currents in rat locus ceruleus neurons. J.Pharmacol.Exp.Ther. 276 137 PMID: 8558423
Snape et al (1999) A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donep. and NXX-066. Neuropharmacology 38 181 PMID: 10193909
Summers and Kaufman (1980) THA- A review of the literature and its use in treatment of five overdose patients. Clin.Toxicol. 16 269 PMID: 6994999
Merck Index 12 9199
关键词: Tacrine hydrochloride, Tacrine hydrochloride supplier, Cholinesterase, inhibitors, inhibits, AChE, Acetylcholinesterase, Esterases, Acetylcholine, Nicotinic, Receptors, nAChR, Muscarinic, Non-selective, Muscarinics, Cholinesterases, 0965, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Tacrine hydrochloride 的部分引用包括:
Rio et al (2010) M3 muscarinic acetylcholine receptor expression confers differential cholinergic modulation to neurochemically distinct hippocampal basket cell subtypes. Mol Cell Endocrinol 30 6011 PMID: 20427660
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