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说明： Inhibitor of smooth muscle cell migration and proliferation
化学名： 3-[Bis(4-methoxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
纯度： ≥99% (HPLC)
生物活性 for TAS 301
TAS 301 is an inhibitor of smooth muscle cell migration and proliferation. Blocks voltage-independent calcium influx and downstream PKC signaling. Inhibits neointimal thickening after balloon catheter injury to the rat common carotid artery.
技术数据 for TAS 301
| 分子量 | 357.4 |
| 公式 | C23H19NO3 |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 193620-69-8 |
| PubChem ID | 9885087 |
| InChI Key | KUEYYIJXBRWZIB-UHFFFAOYSA-N |
| Smiles | O=C2NC1=CC=CC=C1/C2=C(C4=CC=C(OC)C=C4)\C3=CC=C(OC)C=C3 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for TAS 301
参考文献 for TAS 301
参考文献是支持产品生物活性的出版物。
Muranaka et al (1998) TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries. J.Pharmacol.Exp.Ther. 285 1280 PMID: 9618434
Sasaki et al (2000) TAS-301 blocks receptor-operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth factor and platelet-derived growth factor. Jpn.J.Pharmacol. 84 252 PMID: 11138725
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关键词: TAS 301, TAS 301 supplier, TAS301, smooth, muscles, cells, migration, proliferation, blockers, inhibitors, inhibits, voltage-independent, calcium, influx, neointimal, thickening, stenosis, angioplasty, restenosis, Miscellaneous, Compounds, 4521, Tocris Bioscience
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