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TC-G 1000

Cat. No. 5021 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5021 has been discontinued.

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说明： Potent and selective α2D agonist
化学名： 4-(6,7-Dihydro-1,3-dimethylbenzo[c]thien-4-yl)-1H-imidazole maleate
纯度： ≥98% (HPLC)
说明书
引用文献
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文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for TC-G 1000

TC-G 1000 is a potent and selective α2D-adrenoceptor agonist (Ki values are 8.6 pM and 110 nM for rat α2D and α1 receptors respectively and 25, 26 and 100 nM for human α2A, α2C and α2B receptors respectively. Exhibits analgesic activity in a mouse model of abdominal irritation. Orally active.

技术数据 for TC-G 1000

分子量 346.4
公式 C13H14N2S.C4H4O4
储存 Desiccate at RT
纯度 ≥98% (HPLC)
CAS Number 245744-18-7
PubChem ID 90488997
InChI Key OPCJPAYHMCWCGW-BTJKTKAUSA-N
Smiles CC1=C2C(C(C3=CNC=N3)=CCC2)=C(C)S1.O=C(\C=C/C(O)=O)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for TC-G 1000

参考文献是支持产品生物活性的出版物。

Ross et al (2000) α2 adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-Imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene as a high-affinity ligand for the α2D adrenergic receptor. J.Med.Chem. 43 1423 PMID: 10715142

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关键词: TC-G 1000, TC-G 1000 supplier, TC-G1000, potent, selective, adrenergic, receptors, agonists, alpha2d, alpha1, alpha2a, alpha2b, alpha2c, α2d, α2a, α1, α2b, α2c, adrenoceptors, Adrenergic, Alpha-2, Receptors, 5021, Tocris Bioscience

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