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Submit ReviewTC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor (IC50 values are 6 and 40 nM at human and mouse 17β-HSD3 respectively). Displays no activity at 17β-HSD1, 17β-HSD2, ERα, androgen receptors or glucocorticoid receptors.
分子量 | 422.32 |
公式 | C17H12BrNO3S2 |
储存 | Store at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 330203-01-5 |
PubChem ID | 1774851 |
InChI Key | HEFKAUYVLSGPGC-DHDCSXOGSA-N |
Smiles | S=C(S/C(C3=O)=C\C2=CC=C(O)C(Br)=C2)N3C1=CC=C(OC)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Harada et al (2012) Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg.Med.Chem.Lett. 22 504 PMID: 22137341
关键词: TC HSD 21, TC HSD 21 supplier, TCHSD21, 17beta, HSD3, 17b, 17β, hydroxysteroid, type, 3, potent, selective, inhibitors, inhibits, Other, Dehydrogenases, 4575, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
This product guide reviews some of the main areas in cancer metabolism research and lists around 150 products that can be used to investigate metabolic pathways in cancer including:
This poster summarizes the main metabolic pathways in cancer cells and highlights potential targets for cancer therapeutics. Genetic changes and epigenetic modifications in cancer cells alter the regulation of cellular metabolic pathways providing potential cancer therapeutic targets.