TC HSD 21

Discontinued Product

4575 has been discontinued.

View all Other Dehydrogenases products.
说明: Potent and selective 17β-hydroxysteroid dehydrogenase type 3 inhibitor
化学名: 5-[(3-Bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-4-thiazolidinone
纯度: ≥99% (HPLC)
说明书
引用文献
评论
文献 (2)

生物活性 for TC HSD 21

TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor (IC50 values are 6 and 40 nM at human and mouse 17β-HSD3 respectively). Displays no activity at 17β-HSD1, 17β-HSD2, ERα, androgen receptors or glucocorticoid receptors.

技术数据 for TC HSD 21

分子量 422.32
公式 C17H12BrNO3S2
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 330203-01-5
PubChem ID 1774851
InChI Key HEFKAUYVLSGPGC-DHDCSXOGSA-N
Smiles S=C(S/C(C3=O)=C\C2=CC=C(O)C(Br)=C2)N3C1=CC=C(OC)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for TC HSD 21

参考文献是支持产品生物活性的出版物。

Harada et al (2012) Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg.Med.Chem.Lett. 22 504 PMID: 22137341

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关键词: TC HSD 21, TC HSD 21 supplier, TCHSD21, 17beta, HSD3, 17b, 17β, hydroxysteroid, type, 3, potent, selective, inhibitors, inhibits, Other, Dehydrogenases, 4575, Tocris Bioscience

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