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Submit ReviewPotent equilibrative nucleoside transporter 4 (ENT4) inhibitor (IC50 = 74.4 nM). Exhibits 20-fold and 80-fold selectivity for ENT4 over ENT2 and ENT1, respectively.
分子量 | 504.71 |
公式 | C26H48N8O2 |
储存 | Store at RT |
纯度 | ≥98% (HPLC) |
CAS Number | 949467-71-4 |
PubChem ID | 16757265 |
InChI Key | KIZLZYHFIWWKIL-UHFFFAOYSA-N |
Smiles | CC(C)CN(CC(C)C)C2=NC(NCCO)=NC1=C(N(CC(C)C)CC(C)C)N=C(NCCO)N=C12 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Wang et al (2013) Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4). Biochem.Pharmacol. 86 1531 PMID: 24021350
关键词: TC-T 6000, TC-T 6000 supplier, potent, selective, ENT4, inhibitors, inhibits, equilibrative, nucleoside, transporter, 4, Nucleoside, Transporters, 5100, Tocris Bioscience
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