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Submit ReviewTCS HDAC6 20b
说明： Selective HDAC6 inhibitor
化学名： 2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester
纯度： ≥98% (HPLC)
生物活性 for TCS HDAC6 20b
TCS HDAC6 20b is a selective inhibitor of histone deacetylase 6 (HDAC6). Inhibits HCT116 growth in combination with taxol (Cat. No. 1097). Also inhibits growth of MCF-7 cells stimulated by estrogen.
技术数据 for TCS HDAC6 20b
| 分子量 | 480.7 |
| 公式 | C26H44N2O4S |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 956154-63-5 |
| PubChem ID | 23636017 |
| InChI Key | DQZMLPMCOMRJOR-MOVGKWKRSA-N |
| Smiles | O=C([C@@H](NC(OC(C)(C)C)=O)CCCCCSC(C(C)C)=O)NC1(CC3C2)CC(C3)CC2C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for TCS HDAC6 20b
参考文献 for TCS HDAC6 20b
参考文献是支持产品生物活性的出版物。
Itoh et al (2007) Design, synthesis, structure-selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J.Med.Chem. 50 5425 PMID: 17929798
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关键词: TCS HDAC6 20b, TCS HDAC6 20b supplier, TCSHDAC620b, histone, deacetylase, 6, HDAC6, inhibitors, inhibits, selective, Class, II, HDACs, 4805, Tocris Bioscience
1 篇 TCS HDAC6 20b 的引用文献
引用文献是使用了 Tocris 产品的出版物。 TCS HDAC6 20b 的部分引用包括：
Xiaojun et al (2016) Acetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica. Sci Rep 6 32257 PMID: 27577858
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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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