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Discontinued Product
5482 has been discontinued.
View all Post-translational Modifications products.
说明： PAD4 inhibitor
生物活性 for TDFA
Protein arginine deiminase 4 (PAD4) inhibitor (IC50 values are 2.3, 8.5, 26 and 71 μM for PAD4, PAD1, PAD3 and PAD2, respectively).
技术数据 for TDFA
| 分子量 | 448.45 |
| 公式 | C17H29FN6O7 |
| 序列 |
Ac-TD-X (Modifications: Thr-1 = N-terminal Ac, X = N5-(2-fluoro-1-iminoethyl)]-Orn), X-3= C-terminal amide) |
| 储存 | Store at -20°C |
| CAS Number | 1345019-64-8 |
| PubChem ID | 121513865 |
| InChI Key | SOZMHIJABUOUSN-ORMVGFHCSA-N |
| Smiles | [H]N([C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)CF)C(N)=O)C(C)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for TDFA
参考文献 for TDFA
参考文献是支持产品生物活性的出版物。
Jones et al (2012) Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem.Biol. 7 160 PMID: 22004374
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关键词: TDFA, TDFA supplier, PAD4, protein, arginine, deiminase, 4, inhibits, inhibitors, Post-translational, Modifications, 5482, Tocris Bioscience
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