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说明： Potent dCTP pyrophosphatase 1 inhibitor
化学名： 2-[4-[[5,6-Dichloro-2-methyl-4-nitro-1H-benzo[d]-imidazol-1-yl]methyl]phenyl]-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
纯度： ≥98% (HPLC)
生物活性 for TH 1217
TH 1217 is a potent dCTPase pyrophosphatase 1 inhibitor (IC50 = 47 nM).
TH 1217 is not stable in aqueous solution. It is recommended that fresh samples are prepared and used immediately.
许可信息
Sold under license from Thomas Helleday's Foundation for Medical Research and Oxcia AB.
技术数据 for TH 1217
| 分子量 | 491.09 |
| 公式 | C20H17BCl2N4O6 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 1862212-48-3 |
| PubChem ID | 137919863 |
| InChI Key | HWFRCQHNILGMLL-UHFFFAOYSA-N |
| Smiles | CC1=NC2=C([N+]([O-])=O)C(Cl)=C(C=C2N1CC3=CC=C([B-]45OC(C[N+](CC(O5)=O)4C)=O)C=C3)Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for TH 1217
参考文献 for TH 1217
参考文献是支持产品生物活性的出版物。
Llona-Minguez et al (2016) Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1. J.Med.Chem. 59 1140 PMID: 26771665
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关键词: TH 1217, TH 1217 supplier, TH1217, XTP3TPA, dCTP1, pyrophosphatase, diphosphatase, 1, inhibitors, inhibits, potent, nucleotidohydrolase, Other, Hydrolases, 6522, Tocris Bioscience
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