TMPH hydrochloride

Name: TMPH hydrochloride
Brand: Tocris Bioscience
SKU: 2438

Cat. No. 2438 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2438 has been discontinued.

View all Nicotinic Receptors (Non-selective) products.

说明： Neuronal nAChR antagonist

化学名： 2,2,6,6-Tetramethylpiperidin-4-yl heptanoate

纯度： ≥98% (HPLC)

说明书

引用文献 (2)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for TMPH hydrochloride

TMPH hydrochloride is a potent non-competitive antagonist of neuronal nicotinic ACh receptors (nAChRs). Produces long-lasting inhibition of neuronal nAChRs formed by the combination of the most abundant α and β subunits (i.e. α3, α4 and β2, β4 respectively). Displays little inhibition of muscle-type (α1β1γδ) or α7 receptors.

许可信息

Sold under license from the University of Florida Research Foundation Inc.

技术数据 for TMPH hydrochloride

分子量	305.88
公式	C₁₆H₃₁NO₂.HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	849461-91-2
PubChem ID	16079014
InChI Key	XIDDVJIJIFWGIX-UHFFFAOYSA-N
Smiles	CC1(C)NC(C)(C)CC(OC(CCCCCC)=O)C1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for TMPH hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for TMPH hydrochloride

参考文献是支持产品生物活性的出版物。

Papke et al (2005) The effects of subunit composition on the inhibition of nicotinic receptors by the amphipathic blocker 2,2,6,6-tetramethylpiperidin-4-yl heptanoate. Mol.Pharmacol. 67 1977 PMID: 15761116

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关键词: TMPH hydrochloride, TMPH hydrochloride supplier, Neuronal, nicotinic, receptors, antagonists, Acetylcholine, Non-Selective, Subtypes, nAChR, Nicotinic, Receptors, (Non-selective), 2438, Tocris Bioscience

2 篇 TMPH hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 TMPH hydrochloride 的部分引用包括：

Pinnock et al (2015) Nicotine receptors mediating sensorimotor gating and its enhancement by systemic nicotine. J Biomed Sci 9 30 PMID: 25717295

Peng et al (2013) Multiple modes of α7 nAChR noncompetitive antagonism of control agonist-evoked and allosterically enhanced currents. Mol Pharmacol 84 459 PMID: 23839567