trans-4-Hydroxycrotonic acid

Discontinued Product

0538 has been discontinued.

View all Miscellaneous GABA products.
说明: GHB receptor ligand
化学名: trans-4-Hydroxy-2-butenoic acid
纯度: ≥99% (HPLC)
说明书
引用文献
评论
文献 (1)

生物活性 for trans-4-Hydroxycrotonic acid

Binds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself. May be an endogenous ligand.

技术数据 for trans-4-Hydroxycrotonic acid

分子量 102.09
公式 C4H6O3
储存 Desiccate at +4°C
纯度 ≥99% (HPLC)
CAS Number 24587-49-3
PubChem ID 6155526
InChI Key RMQJECWPWQIIPW-OWOJBTEDSA-N
Smiles OC\C=C\C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for trans-4-Hydroxycrotonic acid

参考文献 for trans-4-Hydroxycrotonic acid

参考文献是支持产品生物活性的出版物。

Bourguignon et al (1988) Analogues of γ-hydroxybutyric acid. Synthesis and binding studies. J.Med.Chem. 31 893 PMID: 3361576

Hechler et al (1993) Gamma hydroxybutyrate ligands posses antiDArgic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 264 1406 PMID: 8095552

Vayer et al (1985) Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain. Biochem.Pharmacol. 34 2401 PMID: 4015683

关键词: trans-4-Hydroxycrotonic acid, trans-4-Hydroxycrotonic acid supplier, GHB, receptor, ligand, GABAB, Receptors, GABAA, GABAC, Miscellaneous, GABA, 0538, Tocris Bioscience

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该领域的文献

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GABA Receptors Scientific Review

GABA Receptors Scientific Review

Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.