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Submit ReviewBinds to the γ-hydroxybutyric acid (GHB) receptor with higher affinity than GHB itself. May be an endogenous ligand.
分子量 | 102.09 |
公式 | C4H6O3 |
储存 | Desiccate at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 24587-49-3 |
PubChem ID | 6155526 |
InChI Key | RMQJECWPWQIIPW-OWOJBTEDSA-N |
Smiles | OC\C=C\C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Bourguignon et al (1988) Analogues of γ-hydroxybutyric acid. Synthesis and binding studies. J.Med.Chem. 31 893 PMID: 3361576
Hechler et al (1993) Gamma hydroxybutyrate ligands posses antiDArgic and neuroleptic-like activities. J.Pharmacol.Exp.Ther. 264 1406 PMID: 8095552
Vayer et al (1985) Natural occurrence of trans-gamma hydroxycrotonic acid in rat brain. Biochem.Pharmacol. 34 2401 PMID: 4015683
关键词: trans-4-Hydroxycrotonic acid, trans-4-Hydroxycrotonic acid supplier, GHB, receptor, ligand, GABAB, Receptors, GABAA, GABAC, Miscellaneous, GABA, 0538, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.