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TRC 051384

Cat. No. 4734 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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4734 has been discontinued.

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说明： Inducer of heat shock protein Hsp70
化学名： N-[2-(4-Morpholinyl)ethyl]-N'-[4-[3-[6-(4-morpholinyl)-2-pyridinyl]-1-oxo-2-propen-1-yl]phenyl]urea
纯度： ≥98% (HPLC)
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生物活性 技术数据 说明书 参考文献

生物活性 for TRC 051384

TRC 051384 is a inducer of heat shock protein Hsp70; reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke. Activates heat shock factor-1 and results in elevated chaperone and anti-inflammatory activity. Enhances Hsp72 expression in neurons and glial cells.

技术数据 for TRC 051384

分子量 465.54
公式 C25H31N5O4
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 867164-40-7
PubChem ID 11634093
InChI Key SQTSPANZQDCPLB-CMDGGOBGSA-N
Smiles O=C(C3=CC=C(NC(NCCN4CCOCC4)=O)C=C3)/C=C/C1=CC=CC(N2CCOCC2)=N1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for TRC 051384

参考文献是支持产品生物活性的出版物。

Mohanan et al (2011) Delayed intervention in experimental stroke with TRC051384--a small molecule HSP70 inducer. Neuropharmacology. 60 991 PMID: 21167846

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关键词: TRC 051384, TRC 051384 supplier, TRC051384, potent, inducers, heat, shock, proteins, HSP70, strokes, neuronal, injury, transient, ischemic, stroke, anti-inflammatory, chaperone, Hsp70, 4734, Tocris Bioscience

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