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U 104

Cat. No. 4540 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4540 has been discontinued.

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说明： Potent carbonic anhydrase (CA) IX and XII inhibitor
化学名： 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]-benzesulfonamide
纯度： ≥99% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for U 104

U 104 is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). Inhibits tumor metastasis in the rat 4T1 metastasis model.

技术数据 for U 104

分子量 309.32
公式 C13H12FN3O3S
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 178606-66-1
PubChem ID 310360
InChI Key YJQZNWPYLCNRLP-UHFFFAOYSA-N
Smiles FC1=CC=C(NC(NC2=CC=C(S(=O)(N)=O)C=C2)=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for U 104

参考文献是支持产品生物活性的出版物。

Lou et al (2011) Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Res. 71 3364 PMID: 21415165

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关键词: U 104, U 104 supplier, U104, supplier, potent, carbonic, anhydrase, XI, XII, 9, 12, CA, inhibitors, inhibits, metastatic, metastasis, hypoxic, hypoxia, Carbonic, anhydrases, 4540, Tocris Bioscience

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