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说明： Non-NMDA iGluR antagonist; distinguishes between motoneuron and dorsal root kainate receptors
别名： 3-CBW
化学名： (αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
纯度： ≥98% (HPLC)
生物活性 for UBP 282
AMPA and kainate receptor antagonist. Inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres.
技术数据 for UBP 282
| 分子量 | 333.3 |
| 公式 | C15H15N3O6 |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 544697-47-4 |
| PubChem ID | 6604912 |
| InChI Key | XLRLZPOBHPIDFX-NSHDSACASA-N |
| Smiles | O=C(C=CN1C[C@H](N)C(O)=O)N(CC2=CC=C(C(O)=O)C=C2)C1=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for UBP 282
参考文献 for UBP 282
参考文献是支持产品生物活性的出版物。
More et al (2002) The novel antagonist 3-CBW discriminates between kainate receptors expressed on neonatal rat motoneurones and those on dorsal root C-fibres. Br.J.Pharmacol. 137 1125 PMID: 12429586
More et al (2003) Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br.J.Pharmacol. 138 1093 PMID: 12684265
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关键词: UBP 282, UBP 282 supplier, AMPA/kainate, antagonists, receptors, Glutamate, AMPA, iGluR, Ionotropic, Kainate, UBP282, 3CBW, 3-CBW, Receptors, 1765, Tocris Bioscience
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