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Submit ReviewUCM 707
说明： Potent anandamide transport inhibitor
化学名： (5Z,8Z,11Z,14Z)-N-(3-Furanylmethyl)-5,8,11,14-eicosatetraenamide
生物活性 for UCM 707
UCM 707 is a potent endocannabinoid transport inhibitor. IC50 values are 0.8 and 30 μM for inhibition of the anandamide transporter and FAAH respectively. Ki values are 4700, 67 and > 5000 nM for CB1, CB2 and VR1 receptors respectively. Potentiates hypokinetic and antinociceptive effects of anandamide in vivo.
技术数据 for UCM 707
| 分子量 | 383.57 |
| 公式 | C25H37NO2 |
| 储存 | Desiccate at -20°C |
| CAS Number | 390824-20-1 |
| PubChem ID | 10199993 |
| InChI Key | FZNNBSHTNRBBBD-DOFZRALJSA-N |
| Smiles | O=C(NCC1=COC=C1)CCC\C=C/C\C=C/C/C=C\C/C=C\CCCCC |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for UCM 707
参考文献 for UCM 707
参考文献是支持产品生物活性的出版物。
Lopez-Rodriguez et al (2003) Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors. Eur.J.Med.Chem. 38 403 PMID: 12750028
Lopez-Rodriguez et al (2003) Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase. J.Med.Chem. 46 1512 PMID: 12672252
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关键词: UCM 707, UCM 707 supplier, Potent, anandamide, transporters, inhibitors, inhibits, AMT, Anandamide, cannabinoids, Monoamine, Neurotransmitter, UCM707, Cannabinoid, Transporters, 1966, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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