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Submit ReviewUMB 68
说明： GHB receptor ligand
化学名： Sodium 4-Hydroxy-4methylpentanoate
生物活性 for UMB 68
UMB 68 is a GHB receptor ligand. Exhibits similar receptor afffinity as GHB (IC50 for displacement of 3[H]NCS-382 from GHB receptors is 38 μM compared with 25 μM for GHB). Demonstrates no significant affinity for GABAB receptors and does not exhibit GHB-like behavioral effects in vivo.
技术数据 for UMB 68
| 分子量 | 154.14 |
| 公式 | C6H11NaO3 |
| 储存 | Desiccate at RT |
| CAS Number | 581099-89-0 |
| PubChem ID | 57340483 |
| InChI Key | RKKDHFJDHVHVLY-UHFFFAOYSA-M |
| Smiles | O=C(CCC(C)(O)C)O[Na] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for UMB 68
参考文献 for UMB 68
参考文献是支持产品生物活性的出版物。
Wu et al (2003) A tertiary alcohol analog of γ-hydroxybutyric acid as a specific γ-hydroxybutyric acid receptor ligand. J.Pharmacol.Exp.Ther. 305 675 PMID: 12606613
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关键词: UMB 68, UMB 68 supplier, UMB68, gamma-hydroxybutyric, acid, γ, GHB, receptor, ligands, GABAb, GABAB, Receptors, 5518, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.