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Submit ReviewURB 602
说明： Non-competitive MAGL inhibitor
化学名： N-[1,1'-Biphenyl]-3-yl-carbamic acid cyclohexyl ester
纯度： ≥99% (HPLC)
生物活性 for URB 602
URB 602 is a non-competitive MAGL inhibitor. Exhibits selectivity for MAGL over FAAH, diacylglycerol lipase and COX2. Blocks 2-AG hydrolysis in rat brain slices. Enhances stress-induced analgesia in rats.
技术数据 for URB 602
| 分子量 | 295.38 |
| 公式 | C19H21NO2 |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 565460-15-3 |
| PubChem ID | 10979337 |
| InChI Key | HHVUFQYJOSFTEH-UHFFFAOYSA-N |
| Smiles | O=C(OC1CCCCC1)NC2=CC=CC(C3=CC=CC=C3)=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for URB 602
参考文献 for URB 602
参考文献是支持产品生物活性的出版物。
Hohmann et al (2005) An endocannabinoid mechanism for stress-induced analgesia. Nature. 435 1108 PMID: 15973410
Makara et al (2005) Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. Nat.Neurosci. 8 1139 PMID: 16116451
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关键词: URB 602, URB 602 supplier, URB602, non-competitive, MAGL, inhibitors, inhibits, monoacylglycerol, lipases, 6020, Tocris Bioscience
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