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Voriconazole

Cat. No. 3760 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Triazole antifungal agent
别名： UK 109496
化学名： (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-((1H)-1,2,4-triazol-1-yl)-butan-2-ol
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Voriconazole

Voriconazole is a triazole antifungal agent. Displays potent activity against Candida, Cryptococcus and Aspergillus species.

许可信息

Sold for research purposes under agreement from Pfizer Inc.

技术数据 for Voriconazole

分子量 349.31
公式 C16H14F3N5O
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 137234-62-9
PubChem ID 71616
InChI Key BCEHBSKCWLPMDN-MGPLVRAMSA-N
Smiles O[C@]([C@@H](C)C2=NC=NC=C2F)(C3=C(F)C=C(F)C=C3)CN1C=NC=N1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Voriconazole

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 34.93 100
ethanol 34.93 100

制备储备液 for Voriconazole

以下数据基于产品分子量 349.31。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.86 mL 14.31 mL 28.63 mL
5 mM 0.57 mL 2.86 mL 5.73 mL
10 mM 0.29 mL 1.43 mL 2.86 mL
50 mM 0.06 mL 0.29 mL 0.57 mL

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Reconstitution Calculator

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Dilution Calculator

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参考文献 for Voriconazole

参考文献是支持产品生物活性的出版物。

Marco et al (1998) In vitro activities of voricon. (UK-190-496) and four other antifungal agents against 394 clinical isolates of Candida spp. Antimicrob.Agents Chemother. 42 161 PMID: 9449278

Kappe (1999) Antifungal activity of the new azole UK-109,496 (voriconazole). Mycoses 42 82

If you know of a relevant reference for Voriconazole, please let us know.

按标靶查看相关产品

关键词: Voriconazole, Voriconazole supplier, UK109496, monotriazole, antifungal, agent, Miscellaneous, Pfizer, UK, 109496, Antifungals, 3760, Tocris Bioscience

1 篇 Voriconazole 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Voriconazole 的部分引用包括：

Gyorgy et al (2022) Bile acid- and ethanol-mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis. J Physiol 600 1631-1650 PMID: 35081662

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