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VUF 11222

Cat. No. 5668 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： High affinity non-peptide CXCR3 agonist
化学名： 2'-Bromo-N-[[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl]-N,N-dimethyl-[1,1'-biphenyl]-4-methanaminium iodide
纯度： ≥98% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for VUF 11222

VUF 11222 is a high affinity non-peptide CXCR3 agonist (pKi = 7.2).

技术数据 for VUF 11222

分子量 552.33
公式 C25H31BrIN
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1414376-84-3
PubChem ID 71459294
InChI Key IXXWHYDKYNWDKJ-IUQUCOCYSA-M
Smiles C[N+](CC1=CC=C(C2=CC=CC=C2Br)C=C1)(C)CC3=CC[C@H]4C[C@@H]3C(C)4C.[I-]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for VUF 11222

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 55.23 100
ethanol 5.52 10 温和加热

制备储备液 for VUF 11222

以下数据基于产品分子量 552.33。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.81 mL 9.05 mL 18.11 mL
5 mM 0.36 mL 1.81 mL 3.62 mL
10 mM 0.18 mL 0.91 mL 1.81 mL
50 mM 0.04 mL 0.18 mL 0.36 mL

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参考文献 for VUF 11222

参考文献是支持产品生物活性的出版物。

Wijtmans et al (2012) Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands. J.Med.Chem. 55 10572 PMID: 23150943

If you know of a relevant reference for VUF 11222, please let us know.

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关键词: VUF 11222, VUF 11222 supplier, High, affinity, non-peptide, CXCR3, agonists, Chemokine, CXC, Receptors, 5668, Tocris Bioscience

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