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W-84 dibromide

Cat. No. 0532 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0532 has been discontinued.

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说明： Stabilizer of cholinergic antagonist-receptor complexes
化学名： Hexamethylene-bis-[dimethyl-(3-phthalimidopropyl)ammonium]dibromide
说明书
引用文献
评论 (1)
文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for W-84 dibromide

W-84 dibromide is a stabilizes cholinergic antagonist-receptor complexes by an allosteric effect. Increases the protective effect of atropine against organophosphate poisoning.

技术数据 for W-84 dibromide

分子量 708.53
公式 C32H44Br2N4O4
储存 Store at RT
CAS Number 21093-51-6
PubChem ID 167961
InChI Key DZRJZDQAGMZGGA-UHFFFAOYSA-L
Smiles O=C1N(CCC[N+](C)(C)CCCCCC[N+](C)(C)CCCN(C(C4=C3C=CC=C4)=O)C3=O)C(C2=C1C=CC=C2)=O.[Br-].[Br-]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for W-84 dibromide

参考文献是支持产品生物活性的出版物。

Jepsen et al (1988) Allosteric stabilisation of [3H]-N-methylscopolamine binding in guinea pig myocardium by an antidote against organophosphate intoxication. Pharmacol.Toxicol. 63 163 PMID: 3054859

Mitchelson (1975) Antimuscarinic action of an alkane-bis ammonium compound alone and in combination with (+)-bensetimide. Eur.J.Pharmacol. 33 237 PMID: 1242377

Mohr et al (1992) Equipotent allosteric effect of W84 on [3H]-NMS binding to cardiac muscarinic receptors from guinea-pig, rat and pig. Pharmacol.Toxicol. 70 198 PMID: 1579545

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关键词: W-84 dibromide, W-84 dibromide supplier, antagonists-receptor, complex, stabilizer, Muscarinic, Receptors, Acetylcholine, ACh, Non-selective, Muscarinics, 0532, Tocris Bioscience

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HPLC Pharmacokinetic assay.
By Abhijit Nirwane on 01/10/2018
分析类型： In Vivo
种属： Mouse

Purity is excellent.

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