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WL 47 - dimer

Cat. No. 5978 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5978 has been discontinued.

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说明： High affinity caveolin-1 ligand
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引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for WL 47 - dimer

WL 47 - dimer is a high affinity caveolin-1 (CAV1) ligand (Kd = 23 nM); disrupts caveolin-1 oligomers. Exhibits selectivity for CAV1 over BSA, casein and HEWL.

许可信息

Sold with kind permission of Professor Gregory Weiss

技术数据 for WL 47 - dimer

分子量 1844.3
公式 C80H130N24O18S4
序列 CSWMRLK CSWMRLK*

(Modifications: Disulfide Bridge = 1-1*)

储存 Store at -20°C
PubChem ID 123773278
InChI Key DNQUEMNLAOMZEO-HFXGPFCTSA-N
Smiles [H]N[C@@H](CSSC[C@H](N[H])C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for WL 47 - dimer

参考文献是支持产品生物活性的出版物。

Gilliam et al (2016) Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization. J.Med.Chem. 59 4019 PMID: 27010220

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关键词: WL 47 - dimer, WL 47 - dimer supplier, WL47, dimer, high, affinity, selective, caveolin-1, CAV1, ligands, oligomerization, disrupts, Endocytosis, 5978, Tocris Bioscience

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