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说明： TRPM8 agonist; cooling agent
化学名： N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide
纯度： ≥99% (HPLC)
生物活性 for WS 3
WS 3 is a cooling agent that is an agonist at TRPM8 receptors (EC50 = 3.7 μM).
技术数据 for WS 3
| 分子量 | 211.34 |
| 公式 | C13H25NO |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 39711-79-0 |
| PubChem ID | 62907 |
| InChI Key | VUNOFAIHSALQQH-UHFFFAOYSA-N |
| Smiles | CC1CC(C(NCC)=O)C(C(C)C)CC1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for WS 3
参考文献 for WS 3
参考文献是支持产品生物活性的出版物。
Behrendt et al (2004) Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br.J.Pharmacol. 141 737 PMID: 14757700
Bodding (2007) TRP proteins and cancer. Cell Signal. 19 617 PMID: 17029734
Rovner (2007) Better than mint. C&EN 85 95
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关键词: WS 3, WS 3 supplier, TRPM8, agonists, cooling, agent, Channels, Transient, Receptor, Potential, WS3, TRPM, 2927, Tocris Bioscience
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