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View all Glutamate (Metabotropic) Group II Receptors products.Xanthurenic acid is a shown to selectively activate group II mGlu receptors in transfected HEK293 cells at nanomolar concentrations. Attenuates cAMP formation in mouse cortical slices expressing mGlu2 and mGlu3 receptors.
分子量 | 205.17 |
公式 | C10H7NO4 |
储存 | Store at RT |
纯度 | ≥98% (HPLC) |
CAS Number | 59-00-7 |
PubChem ID | 5699 |
InChI Key | FBZONXHGGPHHIY-UHFFFAOYSA-N |
Smiles | OC1=C2C(C(O)=CC(C(O)=O)=N2)=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Han et al (2007) The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis. J.Insect.Physiol. 53 254 PMID: 17070835
Mauro et al (2010) Xanthurenic acid, a novel endogenous ligand for metabotropic glutamate receptors. Program No. 643.1/F2. 2010 Neuroscience Meeting Pl 2010 (Online)
关键词: Xanthurenic acid, Xanthurenic acid supplier, metabotropic, glutamate, receptors, mGlu, ligands, group, II, 2, mglu2, mglu3, Glutamate, (Metabotropic), Group, Receptors, 4120, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
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