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XCC

Cat. No. 4220 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Adenosine receptor antagonist
化学名： 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for XCC

XCC is an adenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).

技术数据 for XCC

分子量 386.4
公式 C19H22N4O5
储存 Desiccate at RT
纯度 ≥98% (HPLC)
CAS Number 96865-83-7
PubChem ID 126079
InChI Key QTMMGCYGCFXBFI-UHFFFAOYSA-N
Smiles O=C1N(CCC)C(C(NC(C3=CC=C(OCC(O)=O)C=C3)=N2)=C2N1CCC)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for XCC

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 19.32 50

制备储备液 for XCC

以下数据基于产品分子量 386.4。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 5.18 mL 25.88 mL 51.76 mL
2.5 mM 1.04 mL 5.18 mL 10.35 mL
5 mM 0.52 mL 2.59 mL 5.18 mL
25 mM 0.1 mL 0.52 mL 1.04 mL

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产品说明书 for XCC

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for XCC

参考文献是支持产品生物活性的出版物。

Jarvis et al (1989) Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain. Brain Res. 484 111 PMID: 2713675

Sebastiao et al (1990) The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br.J.Pharmacol. 101 453 PMID: 2257444

Thummler and Dunwiddie (2000) Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. J.Neurophysiol. 83 1787 PMID: 10758091

If you know of a relevant reference for XCC, please let us know.

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关键词: XCC, XCC supplier, XCC, adenosine, antagonists, Non-selective, Adenosine, 4220, Tocris Bioscience

1 篇 XCC 的引用文献

引用文献是使用了 Tocris 产品的出版物。 XCC 的部分引用包括：

Wakisaka et al (2017) An Adenosine Receptor for Olfaction in Fish. Curr Biol 27 1437 PMID: 28502661

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