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Submit ReviewZD 2079
Discontinued Product
2154 has been discontinued.
View all Adrenergic β<sub>3</sub> Receptors products.
说明： β3-adrenoceptor agonist
化学名： 4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethoxy]-benzeneacetic acid hydrochloride
纯度： ≥99% (HPLC)
生物活性 for ZD 2079
ZD 2079 is an β3-adrenoceptor agonist. Relaxes rat mesenteric artery and isolated aorta in vitro. Inhibits ob gene expression and circulating leptin levels in lean mice in vivo.
许可信息
Sold with the permission of AstraZeneca UK Ltd.
技术数据 for ZD 2079
| 分子量 | 351.83 |
| 公式 | C18H21NO4.HCl |
| 储存 | Desiccate at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 178600-17-4 |
| PubChem ID | 158793 |
| InChI Key | KCEFVYIWOQSJCH-LMOVPXPDSA-N |
| Smiles | Cl[H].O[C@@H](CNCCOC1=CC=C(CC(O)=O)C=C1)C1=CC=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for ZD 2079
参考文献 for ZD 2079
参考文献是支持产品生物活性的出版物。
Brawley et al (2000) Role of endothelium/nitric oxide in atypical β-adrenoceptor-mediated relaxation in rat isolated aorta. Eur.J.Pharmacol. 398 285 PMID: 10854841
Kozlowska et al (2003) Atypical β-adrenoceptors, different from β3-adrenoceptors, relax the rat isolated mesenteric artery. Br.J.Pharmacol. 140 3 PMID: 12967929
Trayhurn et al (1996) Rapid inhibition of ob gene expression and circulating leptin levels in lean mice by the β3-adrenoceptor agonists BRL 35135A and ZD2079. Biochem.Biophys.Res.Comm. 228 605
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关键词: ZD 2079, ZD 2079 supplier, β3-adrenoceptor, b3-adrenoceptor, β3-adrenergic, b3-adrenergic, agonists, Receptors, ZD2079, AstraZeneca, Adrenergic, Beta-3, 2154, Tocris Bioscience
1 篇 ZD 2079 的引用文献
引用文献是使用了 Tocris 产品的出版物。 ZD 2079 的部分引用包括：
Suárez et al (2014) Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat. Dis Model Mech 7 129 PMID: 24159189
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.