Zimelidine dihydrochloride

Name: Zimelidine dihydrochloride
Brand: Tocris Bioscience
SKU: 1767

Cat. No. 1767 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1767 has been discontinued.

View all 5-HT Transporters products.

说明： Selective 5-HT uptake inhibitor

化学名： (2Z)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyrindinyl)-2-propen-1-amine dihydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献 (1)

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Zimelidine dihydrochloride

5-HT re-uptake inhibitor; selective over noradrenalin and dopamine uptake (IC₅₀ values are 0.33, 8.2 and 12 μM respectively). Modulates nociception and induces hyperglycemia in vivo, and is an orally active antidepressant.

技术数据 for Zimelidine dihydrochloride

分子量	390.15
公式	C₁₆H₁₇BrN₂.2HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	60525-15-7
PubChem ID	6436006
InChI Key	CXGURXWCQYHDIR-ULPVBNQHSA-N
Smiles	Cl[H].Cl[H].CN(C)C\C=C(\C1=CC=C(Br)C=C1)C1=CC=CN=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Zimelidine dihydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Zimelidine dihydrochloride

参考文献是支持产品生物活性的出版物。

Ogren et al (1981) The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta Psychiatr.Scand.Suppl. 290 127 PMID: 6452789

Fasmer et al (1987) Changes in nociception after acute and chronic administration of zimelidine: different effects in the formalin test and substance P behavioural assay. Neuropharmacology 26 309 PMID: 2438584

Sugimoto et al (1999) Involvement of serotonin in zimelidine-induced hyperglycemia in mice. Biol.Pharm.Bull. 22 1240 PMID: 10598036

按标靶查看相关产品

按产品操作查看相关产品

查看全部 5-HT Transporter Inhibitors

关键词: Zimelidine dihydrochloride, Zimelidine dihydrochloride supplier, Selective, 5-HT, reuptake, inhibitors, inhibits, Serotonin, Transporters, SERT, 5-Hydroxytryptamine, Monoamine, Neurotransmitter, 1767, Tocris Bioscience

1 篇 Zimelidine dihydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Zimelidine dihydrochloride 的部分引用包括：

Kim et al (2009) A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation. PLoS One 4 e6044 PMID: 19557182