Tocriscreen Plus

Discontinued Product

This product has been withdrawn from sale and is superseded by Tocriscreen 2.0 Max (Cat. No. 7150)
Description: A library of 1280 biologically active compounds (250 μL 10 mM DMSO solutions)
Datasheet
Citations (4)
Reviews
Literature (1)

Biological Activity for Tocriscreen Plus

A library of 1280 biologically active compounds from the Tocris catalog. Covers a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 250 μL 10 mM DMSO solutions. A smaller volume is available as Tocriscreen Plus Mini (Cat. No. 5841).

Key Format and Product Details for Tocriscreen Plus

  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Compounds arranged 80 per rack with 16 racks per library
  • Pre-dissolved in DMSO
  • Many compounds are exclusive to Tocris
  • Unique library with low overlap
  • Full chemical and biological data available
  • Exceptional purity

Technical Data for Tocriscreen Plus

Storage Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Tocriscreen Plus

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for Tocriscreen Plus

References are publications that support the biological activity of the product.

Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research 21 196 PMID: 20956998

Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44 PMID: 20208034

Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA 107 3546 PMID: 20142487

Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256 PMID: 24409953

Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195 PMID: 26253201

Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142 PMID: 25658371

View Related Products by Target

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4 Citations for Tocriscreen Plus

Citations are publications that use Tocris products. Selected citations for Tocriscreen Plus include:

Lansu et al (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol 13 529 PMID: 28288109

Diamantopoulou et al (2019) Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant. Elife 8 PMID: 31180326

Chen et al (2019) A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells.

Liu et al (2018) Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation. Invest New Drugs PMID: 29297149


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Tocriscreen Compound Libraries

Tocriscreen Compound Libraries

This brochure gives an overview of the unique TocriscreenTM bioactive compound library range, including

  • Tocriscreen 2.0 Compound Library
  • Focused Tocriscreen Libraries
  • Tocriscreen FDA-approved Drug Library
  • Tocriscreen PRO Custom Service