Tocriscreen™ Compound Libraries

The Tocriscreen™ range of bioactive compound libraries are collections of compounds designed for use in screening assays for receptor de-orphaning, target validation, drug re-profiling, tool compound identification and also assay development. Comprised of high-purity compounds selected from the Tocris catalog, these libraries provide wide coverage of cellular targets, including GPCRs, ion channels, kinases, enzymes, nuclear receptors and transporters.

If the libraries listed below do not suit your needs, then please get in touch through our Tocriscreen PRO custom compound library service to discuss your requirements. To request the detailed compound lists for any of the Tocriscreen compound libraries, please complete the compound library inquiry form.

Products
Background
Literature (1)

Libraries

Cat. No. Product Name / Activity
7150 Tocriscreen 2.0 Max
Bioactive compound library for high-throughput screening, high-content screening, target validation and assay development; comprised of 1280 biologically active compounds (250 μL 10 mM DMSO solutions)
7152 Tocriscreen 2.0 Micro
Bioactive compound library for high-throughput screening, high-content screening, target validation and assay development; comprised of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)
7151 Tocriscreen 2.0 Mini
Bioactive compound library for high-throughput screening, high-content screening, target validation and assay development; comprised of 1280 compounds (50 μL 10 mM DMSO solutions)
7350 Tocriscreen Antiviral Library
Antiviral compound library for high throughput screening, target validation, assay development and drug repurposing; contains 240 bioactive compounds (100 μL 10 mM DMSO solutions)
7578 Tocriscreen Epigenetics 3.0
A library of 160 epigenetic compounds (100 μL, 10 mM DMSO solutions) for high throughput screening, high content screening, target validation and assay development
7200 Tocriscreen FDA-Approved Drugs Library
Drug repurposing library; a library of 190 compounds equivalent to active components of drug formulations approved by the FDA (100 μL 10 mM DMSO solutions)
8100 Tocriscreen GPCR Compound Library
A bioactive compound library of 240 GPCR compounds (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening, target validation and assay development
7844 Tocriscreen Kinase Inhibitor 3.0
A bioactive compound library of 210 kinase inhibitors (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening, target validation and assay development
7340 Tocriscreen Stem Cell Library
A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling
The Tocriscreen compound libraries are composed of biologically active compounds that have proven pharmacological activity against GPCRs, ion channels, kinases, enzymes, nuclear receptors and transporters.
  • Compounds ready-to-use in DMSO (10 mM)
  • Key research areas are covered including Cancer, Epigenetics, Neuroscience and Stem Cells
  • Includes commonly used standards and the latest research tools, as well pharmacologically active components of FDA-approved drug formulations
  • Compounds available for re-supply from the Tocris catalog

Resources for Tocriscreen Compound Libraries


The Chemical Diversity of the Tocriscreen Kinase Inhibitor 3.0

The images show the overlapping chemical space of the 210 compounds in the Tocriscreen Kinase Inhibitor 3.0 compound library (green dots) in relation to the chemical space occupied by the ChEMBL Kinase Inhibitors (grey dots). Each dot represents a unique fingerprint generated from each compound's 3D molecular structure. The even distribution of the fingerprints of the compounds in the Tocriscreen Kinase Inhibitor 3.0 compound library highlights the chemical diversity of this library.

Webinar: Chemical Genomics - Undruggables and the Quest for Therapeutics

This webinar brings together experts to discuss chemical genomics and the advances and promises it brings to therapeutic discovery. The use of compound libraries and the possibilities for drug repurposing are examined, and the potential of patient lead approaches to identify novel targets with chemical genomics are considered.

Watch Chemical Genomics Webinar
Chemical Genomics - Undruggables and the Quest for Therapeutics

Literature for Tocriscreen™ Compound Libraries

Tocris offers the following scientific literature for Tocriscreen™ Compound Libraries to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


Tocriscreen Compound Libraries

Tocriscreen Compound Libraries

This brochure gives an overview of the unique TocriscreenTM bioactive compound library range, including

  • Tocriscreen 2.0 Compound Library
  • Focused Tocriscreen Libraries
  • Tocriscreen FDA-approved Drug Library
  • Tocriscreen PRO Custom Service