VIP Receptors
Vasoactive intestinal peptide (VIP) receptors are a group of Gs -protein-coupled receptors that are currently divided into two subtypes; VPAC1 and VPAC2. They are widely distributed throughout the central nervous system.
VIP Receptor Agonists |
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|---|---|
| Cat. No. | Product Name / Activity |
| 2711 | Bay 55-9837 |
| Potent and selective VPAC2 agonist | |
| 1911 | VIP (human, rat, mouse, rabbit, canine, porcine) |
| Involved in neurotransmission and smooth muscle relaxation | |
VIP Receptor Antagonists |
|
| Cat. No. | Product Name / Activity |
| 3054 | [D-p-Cl-Phe6,Leu17]-VIP |
| Selective VIP receptor antagonist | |
Vasoactive intestinal peptide (VIP) receptors are a group of Gs-protein-coupled receptors that are currently divided into two subtypes; VPAC1 and VPAC2. They are widely distributed throughout the central nervous system and are also found in peripheral organs including the liver, lung, intestine, skeletal muscle, heart and kidney.
VPAC1 and VPAC2 have diverse biological actions including promotion of neuronal survival, regulation of glycogen metabolism, stimulation of prolactin release from the pituitary and catecholamine release from the adrenal medulla, and inhibition of IL-2-mediated T-cell proliferation. The human genes encoding VPAC1 and VPAC2 receptor have been located on chromosomes 3p22 and 7q36.3 respectively.