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Description: 5-, 12-, 15-Lipoxygenase inhibitor
Chemical Name: 2-(1-Thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate
Purity: ≥99% (HPLC)
Biological Activity for 2-TEDC
2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC50 values are 0.09, 0.013 and 0.5 μM respectively).
Technical Data for 2-TEDC
| M. Wt | 315.34 |
| Formula | C16H13NO4S |
| Storage | Desiccate at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 132465-10-2 |
| PubChem ID | 6069552 |
| InChI Key | KCGLTUBCAGZLHP-XYOKQWHBSA-N |
| Smiles | OC1=C(O)C=C(\C=C(/C#N)C(=O)OCCC2=CC=CS2)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 2-TEDC
References for 2-TEDC
References are publications that support the biological activity of the product.
Cho et al (1991) Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 34 1503 PMID: 2016727
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Keywords: 2-TEDC, 2-TEDC supplier, 5-lipoxygenase, 12-lipoxygenase, 15-Lipoxygenase, inhibitors, inhibits, Oxygenases, Oxidases, 5-LOX, 12-LOX, 15-LOX, Lipoxygenase, 0645, Tocris Bioscience
Citations for 2-TEDC
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Currently there are no citations for 2-TEDC.
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