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Submit Review5-Nonyloxytryptamine oxalate
Description: Selective 5-HT1B agonist
Purity: ≥99% (HPLC)
Biological Activity for 5-Nonyloxytryptamine oxalate
5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Mimics polysialic acid activity, stimulates neuritogenesis, myelination and Schwann cell migration in vitro.
Technical Data for 5-Nonyloxytryptamine oxalate
| M. Wt | 392.49 |
| Formula | C19H30N2O.C2H2O4 |
| Storage | Store at RT |
| Purity | ≥99% (HPLC) |
| CAS Number | 157798-13-5 |
| PubChem ID | 10126593 |
| InChI Key | JORSCLBFSAAOFR-UHFFFAOYSA-N |
| Smiles | OC(=O)C(O)=O.CCCCCCCCCOC1=CC=C2NC=C(CCN)C2=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 5-Nonyloxytryptamine oxalate
References for 5-Nonyloxytryptamine oxalate
References are publications that support the biological activity of the product.
Glennon et al (1994) 5-(Nonyloxy)tryptamine: a novel high affinity-5-HT1Dβ serotonin receptor agonist. J.Med.Chem. 37 2828 PMID: 8071931
Glennon et al (1996) Binding of O-Alkyl derivatives of serotonin at human 5-HT1Dβ receptors. J.Med.Chem. 39 314 PMID: 8568822
Loers et al (2013) Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J.Neurochem. 128 88 PMID: 23957498
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Keywords: 5-Nonyloxytryptamine oxalate, 5-Nonyloxytryptamine oxalate supplier, Selective, 5-HT1B, agonists, Serotonin, Receptors, 0901, Tocris Bioscience
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
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