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Submit Review6-Nitroindazole
Description: nNOS inhibitor
Biological Activity for 6-Nitroindazole
nNOS inhibitor. Less potent antinociceptive than the 7-nitro analogue (0602), but is equally potent in relaxing smooth muscle independently of its inhibition of NO synthase.
Technical Data for 6-Nitroindazole
| M. Wt | 163.14 |
| Storage | Desiccate at +4°C |
| CAS Number | 7597-18-4 |
| Smiles | O=[N+](C1=CC=C2C(NN=C2)=C1)[O-] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 6-Nitroindazole
Certificate of Analysis is currently unavailable on-line.
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References for 6-Nitroindazole
References are publications that support the biological activity of the product.
Medhurst et al (1994) NO synthase inhibitors 7- and 6-nitroindazole relax smooth muscle in vitro. Eur.J.Pharmacol. 256 R5 PMID: 7517888
Moore et al (1993) Characterisation of the novel NO synthase inhibitor 7-nitroindazole and related indazoles: antinociceptive and cardiovascular effects. Br.J.Pharmacol. 110 219 PMID: 7693278
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Keywords: 6-Nitroindazole, 6-Nitroindazole supplier, nNOS, 0710, Tocris Bioscience
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