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Description: Non-selective NOS inhibitor. Sodium salt of 7-nitroindazole (Cat. No. 0602)
Chemical Name: 7-Nitroindazole monosodium salt
Purity: ≥98%
Biological Activity for 7-NINA
7-NINA is a sodium salt of the non-selective NOS inhibitor 7-nitroindazole (Cat. No. 0602).
Technical Data for 7-NINA
| M. Wt | 185.12 |
| Formula | C7H4N3O2Na |
| Storage | Desiccate at -20°C |
| Purity | ≥98% |
| CAS Number | 161467-34-1 |
| PubChem ID | 16760594 |
| InChI Key | DJMLKKIIBMJGIQ-UHFFFAOYSA-N |
| Smiles | [Na+].[O-][N+](=O)C1=C2[N-]N=CC2=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 7-NINA
References for 7-NINA
References are publications that support the biological activity of the product.
O'Neill et al (1996) Neuroprotective effects of 7-nitroindazole in the gerbil model of global cerebral ischaemia. Eur.J.Pharmacol. 310 115 PMID: 8884206
Silva et al (1995) Increased striatal DA efflux in vivo following inhibition of cerebral nitric oxide synthase by the novel monosodium salt of 7-nitroindazole. Br.J.Pharmacol. 114 257 PMID: 7533610
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Keywords: 7-NINA, 7-NINA supplier, Non-Selective, NOS, Nitric, Oxide, Signaling, Signalling, iNOS, nNOS, eNOS, NO, Synthases, Non-selective, 0800, Tocris Bioscience
2 Citations for 7-NINA
Citations are publications that use Tocris products. Selected citations for 7-NINA include:
Fakira et al (2012) Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice. J Neurosci 51 22 PMID: 22789621
Messlinger et al (2000) Involvement of nitric oxide in the modulation of dural arterial blood flow in the rat. Br J Pharmacol 129 1397 PMID: 10742295
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