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Submit ReviewBNTX maleate
Discontinued Product
0899 has been discontinued.
Description: Standard δ1 selective antagonist
Chemical Name: 7-Benzylidenenaltrexone maleate
Purity: ≥99% (HPLC)
Biological Activity for BNTX maleate
BNTX maleate is a standard selective δ1 opioid receptor antagonist. Also inhibits neurogenic ion transport mediated by a putative novel opioid receptor in porcine ileal mucosa.
Technical Data for BNTX maleate
| M. Wt | 545.59 |
| Formula | C27H27NO4.C4H4O4 |
| Storage | Desiccate at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 864461-31-4 |
| PubChem ID | 71296994 |
| InChI Key | GKHUUKGUNNYVGB-LQDKARLYSA-N |
| Smiles | OC(=O)\C=C/C(O)=O.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)C\C(=C/C1=CC=CC=C1)C2=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for BNTX maleate
References for BNTX maleate
References are publications that support the biological activity of the product.
Hammond et al (1995) Antinociception and d-1 opioid receptors in the rat spinal cord: studies with intrathecal 7-benzylidenenaltrexone. J.Pharmacol.Exp.Ther. 274 1317 PMID: 7562504
Poonyachoti et al (2001) Pharmacological evidence for a 7-benzylidenenaltrexone-preferring opioid receptor mediating the inhibitory actions of peptidic δ- and μ-opioid agonists on neurogenic ion transport in porcine ileal mucosa. J.Pharmacol.Exp.Ther. 297 672 PMID: 11303057
Portoghese et al (1992) A δ1-opioid receptor antagonist: 7-benzylidenenaltrexone. Eur.J.Pharmacol. 218 195 PMID: 1327826
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Keywords: BNTX maleate, BNTX maleate supplier, δ1-opioid, delta1-opioid, selective, antagonists, DOP, Receptors, OP1, Delta, Opioid, 0899, Tocris Bioscience
1 Citation for BNTX maleate
Citations are publications that use Tocris products. Selected citations for BNTX maleate include:
Gomes et al (2000) Heterodimerization of μ and δ opioid receptors: A role in opiate synergy. J Cereb Blood Flow Metab 20 RC110 PMID: 11069979
Reviews for BNTX maleate
Average Rating: 5 (Based on 1 Review.)
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42 perturbagens used the zebrafish DASPEI screen.
By
Anonymous on 12/17/2019
Assay Type: In Vivo
Species: Other
Cell Line/Tissue: larvae
Zebrafish larvae were placed into 48-well plates and used the DASPEI screen by 42 perturbagens drugs, including this compound
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