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Submit ReviewCanrenone
Description: Mineralocorticoid receptor antagonist
Chemical Name: (17α)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid γ-lactone
Purity: ≥98% (HPLC)
Biological Activity for Canrenone
Canrenone is a mineralocorticoid receptor antagonist. Active metabolite of spironolactone (Cat. No. 2968).
Technical Data for Canrenone
| M. Wt | 340.46 |
| Formula | C22H28O3 |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 976-71-6 |
| PubChem ID | 13789 |
| InChI Key | UJVLDDZCTMKXJK-WNHSNXHDSA-N |
| Smiles | O=C1CC[C@@]2(C)C(C=C[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@]54OC(CC5)=O)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Canrenone
References for Canrenone
References are publications that support the biological activity of the product.
Delyani et al (2000) Mineralocorticoid receptor antagonists: the evolution of utility and pharmacology. Kidney Int. 57 1408 PMID: 10760075
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Keywords: Canrenone, Canrenone supplier, Mineralocorticoid, receptor, antagonists, Aldosterone, Receptors, Receptor, 3281, Tocris Bioscience
1 Citation for Canrenone
Citations are publications that use Tocris products. Selected citations for Canrenone include:
Verma et al (2016) Spironolactone blocks Epstein-Barr virus production by inhibiting EBV SM protein function. Proc Natl Acad Sci U S A 113 3609 PMID: 26976570
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