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CD 1530

Cat. No. 2554 3 Citations Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: Potent and selective RARγ agonist
Chemical Name: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid
Purity: ≥98% (HPLC)
Datasheet
Citations (3)
Reviews
Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for CD 1530

CD 1530 is a potent and selective RARγ receptor agonist (Ki values are 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively). Activates transcriptional activity (AC50 = 1.8 nM).

Compound Libraries for CD 1530

CD 1530 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for CD 1530

M. Wt 398.49
Formula C27H26O3
Storage Store at +4°C
Purity ≥98% (HPLC)
CAS Number 107430-66-0
PubChem ID 24868309
InChI Key VCQGNUWOMLYNNG-UHFFFAOYSA-N
Smiles OC(C(C1(C[C@@H]2C3)C[C@H](C2)C[C@H]3C1)=C4)=CC5=C4C=C(C6=CC=C(C(O)=O)C=C6)C=C5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CD 1530

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.84 100

Preparing Stock Solutions for CD 1530

The following data is based on the product molecular weight 398.49. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.51 mL 12.55 mL 25.09 mL
5 mM 0.5 mL 2.51 mL 5.02 mL
10 mM 0.25 mL 1.25 mL 2.51 mL
50 mM 0.05 mL 0.25 mL 0.5 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets for CD 1530

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References for CD 1530

References are publications that support the biological activity of the product.

Thacher et al (2000) Therapeutic applications for ligands of retinoid receptors. Curr.Pharmaceut.Des. 6 25

If you know of a relevant reference for CD 1530, please let us know.

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Keywords: CD 1530, CD 1530 supplier, Potent, selective, RARγ, RARgamma, agonists, RAMBA, Retinoic, Acid, Receptors, CD1530, 2554, Tocris Bioscience

3 Citations for CD 1530

Citations are publications that use Tocris products. Selected citations for CD 1530 include:

Duprey-Díaz et al (2016) Exogenous Modulation of Retinoic Acid Signaling Affects Adult RGC Survival in the Frog Visual System afterOptic Nerve Injury PLoS One 11 e0162626 PMID: 27611191

Nguyen et al (2017) Retinoic acid receptor regulation of epimorphic and homeostatic regeneration in the axolotl. Development 144 601 PMID: 28087637

Garnaas et al (2012) Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Dev Biol 372 178 PMID: 22982668

Do you know of a great paper that uses CD 1530 from Tocris? Please let us know.

Reviews for CD 1530

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Retinoid Receptors Scientific Review

Retinoid Receptors Scientific Review

Written by Alexander Moise, this review summarizes the nature of retinoid receptors, their isotype and isoform variants and modulation of retinoid signaling. Compounds available from Tocris are listed.