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Submit ReviewCoenzyme Q10
Description: Antioxidant
Chemical Name: 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
Purity: ≥99% (HPLC)
Biological Activity for Coenzyme Q10
Coenzyme Q10 is a component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Coenzyme Q10 displays neuroprotective activity. In an animal model of Huntington's disease, Coenzyme Q10 extends survival and delays disease; this effect is more pronounced when combined with Remacemide hydrochloride (Cat. No. 1622). Ferroptosis inhibitor.
Technical Data for Coenzyme Q10
| M. Wt | 863.34 |
| Formula | C59H90O4 |
| Storage | Store at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 303-98-0 |
| PubChem ID | 5281915 |
| InChI Key | ACTIUHUUMQJHFO-UPTCCGCDSA-N |
| Smiles | O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=C(C)C1=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Coenzyme Q10
References for Coenzyme Q10
References are publications that support the biological activity of the product.
Shults (2003) Coenzyme Q10 in neurodegenerative diseases. Curr.Med.Chem. 10 1917 PMID: 12871093
Young et al (2007) Coenzyme Q10: a review of its promise as a neuroprotectant. CNS Spectr. 12 62 PMID: 17192765
Yang and Stockwell et al (2016) Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 26 165 PMID: 26653790
Ferrante et al (2002) Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J.Neurosci. 22 1592 PMID: 11880489
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Keywords: Coenzyme Q10, Coenzyme Q10 supplier, Antioxidant, CoenzymeQ10, Antioxidants, Ferroptosis, 3003, Tocris Bioscience
1 Citation for Coenzyme Q10
Citations are publications that use Tocris products. Selected citations for Coenzyme Q10 include:
Martin et al (2014) Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol 7 101 PMID: 23653115
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