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Submit Review1710 has been discontinued.
View all Adenosine A<sub>2B</sub> Receptors products.CV 1808 is an adenosine A2 receptor agonist. Coronary vasodilator, antihypertensive and antipsychotic following systemic administration in vivo.
M. Wt | 358.36 |
Formula | C16H18N6O4 |
Storage | Desiccate at +4°C |
Purity | ≥99% (HPLC) |
CAS Number | 53296-10-9 |
PubChem ID | 6917803 |
InChI Key | SCNILGOVBBRMBK-SDBHATRESA-N |
Smiles | O[C@@H]1[C@@H](CO)O[C@@H](N(C=N3)C2=C3C(N)=NC(NC4=CC=CC=C4)=N2)[C@@H]1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Abiru et al (1991) The antihypertensive effect of 2-alkynyladenosines and the selective affinity for adenosine A2 receptors. Eur.J.Pharmacol. 196 69 PMID: 1874281
Martin et al (1993) Adenosine agonists reduce conditioned avoidance responding in the rat. Pharmacol.Biochem.Behav. 45 951 PMID: 8105493
Marumoto et al (1975) Synthesis and coronary vasodilating activity of 2-substituted adenosines. Chem.Pharm.Bull. 23 759 PMID: 1182861
Keywords: CV 1808, CV 1808 supplier, Non-Selective, adenosines, A2, receptor, agonists, A2B, Receptors, A2A, CV1808, Adenosine, 1710, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for CV 1808 include:
Kan et al (2012) Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol 86 10338 PMID: 22787201
Baba et al (2018) Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation. J Bone Miner Res 33 1785 PMID: 29893999
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