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Submit ReviewDesloratadine
Discontinued Product
5958 has been discontinued.
View all Histamine H<sub>1</sub> Receptors products.
Description: High affinity H1 antagonist; anti-inflammatory
Chemical Name: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Purity: ≥99% (HPLC)
Biological Activity for Desloratadine
Desloratadine is a high affinity histamine H1 receptor antagonist (Ki = 0.87 nM); active metabolite of loratadine (Cat. No. 1944). Anti-inflammatory.
Technical Data for Desloratadine
| M. Wt | 310.82 |
| Formula | C19H19ClN2 |
| Storage | Store at +4°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 100643-71-8 |
| PubChem ID | 124087 |
| InChI Key | JAUOIFJMECXRGI-UHFFFAOYSA-N |
| Smiles | ClC1=CC=C2C(CCC3=C(/C2=C4CCNCC\4)N=CC=C3)=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Desloratadine
References for Desloratadine
References are publications that support the biological activity of the product.
Henz (2001) The pharmacologic profile of desloratadine: a review. Allergy 56 7 PMID: 11243504
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Keywords: Desloratadine, Desloratadine supplier, histamine, H1, receptors, antagonists, histaminergic, anti-inflammatory, hay, fever, allergic, rhinitis, chornic, urticaria, Histamine, Receptors, 5958, Tocris Bioscience
Citations for Desloratadine
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Currently there are no citations for Desloratadine.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Histamine Receptors Scientific Review
Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.