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Submit ReviewDesmethyl-YM 298198
Discontinued Product
2447 has been discontinued.
View all Glutamate (Metabotropic) Group I Receptors products.
Description: Derivative of mGlu1 antagonist YM 298198 (Cat. No. 2448)
Chemical Name: 6-Amino-N-cyclohexyl-3-methylthiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride
Purity: ≥98% (HPLC)
Biological Activity for Desmethyl-YM 298198
Desmethyl-YM 298198 is a derivative of the mGlu1-selective antagonist YM 298198 (Cat. No. 2448).
Licensing Information
Sold with the permission of Astellas Pharma Inc.
Technical Data for Desmethyl-YM 298198
| M. Wt | 364.89 |
| Formula | C17H20N4OS.HCl |
| Storage | Desiccate at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 1177767-57-5 |
| PubChem ID | 16759180 |
| InChI Key | SWKZWXJQIDXGLX-UHFFFAOYSA-N |
| Smiles | Cl.CC1=C(SC2=NC3=CC=C(N)C=C3N12)C(=O)NC1CCCCC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Desmethyl-YM 298198
References for Desmethyl-YM 298198
References are publications that support the biological activity of the product.
Kohara et al (2005) Radioligand binding properties and pharmacological characterization of 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]-benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective and noncompetitive antagonist of metabo J.Pharmacol.Exp.Ther. 315 163 PMID: 15976016
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Keywords: Desmethyl-YM 298198, Desmethyl-YM 298198 supplier, Derivative, mGlu1, mGluR1, antagonists, YM, 298198, Group, I, Receptors, Glutamate, Metabotropic, Desmethyl-YM298198, (Metabotropic), 2447, Tocris Bioscience
Citations for Desmethyl-YM 298198
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Currently there are no citations for Desmethyl-YM 298198.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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