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View all Non-selective Ionotropic Glutamate products.Sodium salt of the broad spectrum EAA ligand DL-AP4.
M. Wt | 205.08 |
Formula | C4H9NNaO5P |
Storage | Desiccate at RT |
Purity | ≥99% (HPLC) |
CAS Number | 1263093-79-3 |
PubChem ID | 52974248 |
InChI Key | IGWPQOULJIILQQ-UHFFFAOYSA-M |
Smiles | [Na+].NC(CCP(O)([O-])=O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Evans et al (1979) Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. Br.J.Pharmacol. 67 591 PMID: 316343
Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024
Keywords: DL-AP4 Sodium salt, DL-AP4 Sodium salt supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Non-selective, mGlu, 3699, Tocris Bioscience
Citations are publications that use Tocris products. Selected citations for DL-AP4 Sodium salt include:
Sato and Kefalov (2016) cis Retinol oxidation regulates photoreceptor access to the retina visual cycle and cone pigment regeneration. J Physiol 594 6753 PMID: 27385534
Zhou et al (2015) Autophagy supports color vision. Autophagy 11 1821 PMID: 26292183
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Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.