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Submit ReviewDL-AP7
Description: Selective NMDA antagonist
Chemical Name: DL-2-Amino-7-phosphonoheptanoic acid
Biological Activity for DL-AP7
DL-AP7 is a first generation phosphono NMDA antagonist. Anticonvulsant.
Technical Data for DL-AP7
| M. Wt | 225.18 |
| Formula | C7H16NO5P |
| Storage | Store at RT |
| CAS Number | 85797-13-3 |
| PubChem ID | 3122 |
| InChI Key | MYDMWESTDPJANS-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)CCCCCP(O)(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for DL-AP7
References for DL-AP7
References are publications that support the biological activity of the product.
Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024
Meldrum and Chapman (1994) Competitive NMDA antagonists as drugs. In The NMDA Receptor (2nd edition). Eds. G. L. Col 457
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Keywords: DL-AP7, DL-AP7 supplier, Selective, Specific, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGlu, Ionotropic, 78966-69-5, 0104, Tocris Bioscience
2 Citations for DL-AP7
Citations are publications that use Tocris products. Selected citations for DL-AP7 include:
Stevens et al (2010) Light-evoked NMDA receptor-mediated currents are reduced by blocking D-serine synthesis in the salamander retina. Neuroreport 21 239 PMID: 20101193
Gustafson et al (2007) Endogenous D-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina. J Neurophysiol 98 122 PMID: 17507508
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