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Submit ReviewDZNep HCl
Description: 3-Deazaneplanocin A hydrochloride synthesized to Ancillary Material Grade
Chemical Name: (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride
Purity: ≥98%
Biological Activity for DZNep HCl
DZNep-RMU is an Ancillary Material Grade version of product 3-Deazaneplanocin A hydrochloride (Cat. No. 4703). Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.
<Find out more about our Ancillary Material Grade product range.
Technical Data for DZNep HCl
| M. Wt | 298.73 |
| Formula | C12H14N4O3.HCl |
| Storage | Store at -20°C(±5°C) |
| Purity | ≥98% |
| CAS Number | 120964-45-6 |
| InChI Key | UNSKMHKAFPRFTI-FDKLLANESA-N |
| Smiles | OCC([C@@H](O)[C@H]1O)=C[C@H]1N2C=NC3=C(N)N=CC=C32.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for DZNep HCl
Certificate of Analysis is currently unavailable on-line.
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References for DZNep HCl
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Literature in this Area
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Stem Cell Research Product Guide
This product guide provides a background to the use of small molecules in stem cell research and lists over 200 products for use in:
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- Differentiation
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- Organoid Generation
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Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
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Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.
Stem Cells Poster
Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.