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Submit ReviewGlucagon (Human, Porcine)
Description: Endogenous glucagon receptor agonist
Purity: ≥95% (HPLC)
Biological Activity for Glucagon (Human, Porcine)
Glucagon (Human, Porcine) is an endogenous glucagon receptor agonist; regulates blood glucose.
Technical Data for Glucagon (Human, Porcine)
| M. Wt | 3482.78 |
| Formula | C153H225N43O49S |
| Sequence | HSQGTFTSDYSKYLDSRRAQDFVQWLMNT |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 16941-32-5 |
| PubChem ID | 16133817 |
| InChI Key | MASNOZXLGMXCHN-ZLPAWPGGSA-N |
| Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Glucagon (Human, Porcine)
| Solubility | Soluble to 1 mg/ml in water |
Product Datasheets for Glucagon (Human, Porcine)
References for Glucagon (Human, Porcine)
References are publications that support the biological activity of the product.
Thomsen et al (1972) The amino acid sequence of human glucagon. FEBS Lett. 21 315 PMID: 11946536
Zhou et al (2017) A novel glucagon-like peptide-1/glucagon receptor dual agonist exhibits weight-lowering and diabetes-protective effects. Eur.J.Med.Chem. 138 1158 PMID: 28772236
Mayo et al (2003) International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol Rev. 55 167 PMID: 12615957
If you know of a relevant reference for Glucagon (Human, Porcine), please let us know.
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Keywords: Glucagon (Human, Porcine), Glucagon (Human, Porcine) supplier, Endogenous, glucagon, receptor, agonists, agonism, pancreatic, peptide, Glucagon, Receptor, 6927, Tocris Bioscience
1 Citation for Glucagon (Human, Porcine)
Citations are publications that use Tocris products. Selected citations for Glucagon (Human, Porcine) include:
Jing et al (2023) High glucose-induced glucagon resistance and membrane distribution of GCGR revealed by super-resolution imaging. iScience 26 105967 PMID: 36824278
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.