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Submit ReviewICI 154,129
Discontinued Product
0827 has been discontinued.
Description: δ selective peptide antagonist
Biological Activity for ICI 154,129
ICI 154,129 is a selective δ opioid antagonist.
Licensing Information
Sold with the permission of AstraZeneca UK Ltd.
Technical Data for ICI 154,129
| M. Wt | 638.83 |
| Formula | C34H46N4O6S |
| Sequence |
YGFL (Modifications: Tyr-1 = N,N-diallyl-Tyr, Gly-2 - Phe-3 peptide bond replaced with Psi-(CH2S)) |
| Storage | Desiccate at -20°C |
| CAS Number | 83420-94-4 |
| PubChem ID | 3035055 |
| InChI Key | CZRZYRKTYLLLRL-DTXPUJKBSA-N |
| Smiles | CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)SCCNC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)N(CC=C)CC=C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for ICI 154,129
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Please contact Customer Service
References for ICI 154,129
References are publications that support the biological activity of the product.
Shaw et al (1982) Selective antagonists at the opiate delta-receptor. Life Sci. 31 1259 PMID: 6128652
Rees and Hunter (1990) Opioid Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch. 3 805
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Keywords: ICI 154,129, ICI 154,129 supplier, δ-opioid, delta-opioid, selective, peptide, antagonists, DOP, Receptors, OP1, ICI154129, AstraZeneca, Delta, Opioid, 0827, Tocris Bioscience
1 Citation for ICI 154,129
Citations are publications that use Tocris products. Selected citations for ICI 154,129 include:
Jiang et al (2015) Analgesic roles of peripheral intrinsic met-enkephalin and dynorphin A in long-lasting inflammatory pain induced by complete Freund's adjuvant in rats. J Pharmacol Exp Ther 9 2344 PMID: 26136984
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